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cerc24  (Croda International Plc)

 
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    Structured Review

    Croda International Plc cerc24
    Integrated chromatograms, stability, and specificity of the liquid chromatography-mass spectrometry (LC-MS/MS) ceramide quantification assay. During the 5-minute run, Mobile Phase A comprised 10 mM ammonium formate and 0.1% formic acid in LC-MS grade water. Mobile Phase B contained 10 mM ammonium formate and 0.1% formic acid in LC-MS grade water/acetonitrile/isopropanol (5%: 47.5%: 47.5%) (A) . Ceramide metabolites and internal standards were separated adequately based on molecular weights and polarities ( B - C ). The stability of ceramide metabolites over three freeze/thaw cycles showed percentage changes represented by blue, orange, and grey bars after 24, 48, and 72 h, respectively. Quality control levels confirmed percentage changes within ± 7% for all metabolites CerC16:0 ( D ), CerC18:0 ( E ), CerC22:0 ( F ), <t>CerC24:0</t> ( G ), and CerC24:1 ( H ). Overlaid chromatograms of blank samples ( I ) confirmed method specificity, showing no interfering peaks at the respective retention times for ceramide metabolites. IS, Internal Standard; %change, stability
    Cerc24, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 93/100, based on 35 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cerc24/product/Croda International Plc
    Average 93 stars, based on 35 article reviews
    cerc24 - by Bioz Stars, 2026-02
    93/100 stars

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    1) Product Images from "Circulating ceramide levels and ratios in Emirati youth under 18 years: associations with cardiometabolic risk factors"

    Article Title: Circulating ceramide levels and ratios in Emirati youth under 18 years: associations with cardiometabolic risk factors

    Journal: Lipids in Health and Disease

    doi: 10.1186/s12944-024-02080-6

    Integrated chromatograms, stability, and specificity of the liquid chromatography-mass spectrometry (LC-MS/MS) ceramide quantification assay. During the 5-minute run, Mobile Phase A comprised 10 mM ammonium formate and 0.1% formic acid in LC-MS grade water. Mobile Phase B contained 10 mM ammonium formate and 0.1% formic acid in LC-MS grade water/acetonitrile/isopropanol (5%: 47.5%: 47.5%) (A) . Ceramide metabolites and internal standards were separated adequately based on molecular weights and polarities ( B - C ). The stability of ceramide metabolites over three freeze/thaw cycles showed percentage changes represented by blue, orange, and grey bars after 24, 48, and 72 h, respectively. Quality control levels confirmed percentage changes within ± 7% for all metabolites CerC16:0 ( D ), CerC18:0 ( E ), CerC22:0 ( F ), CerC24:0 ( G ), and CerC24:1 ( H ). Overlaid chromatograms of blank samples ( I ) confirmed method specificity, showing no interfering peaks at the respective retention times for ceramide metabolites. IS, Internal Standard; %change, stability
    Figure Legend Snippet: Integrated chromatograms, stability, and specificity of the liquid chromatography-mass spectrometry (LC-MS/MS) ceramide quantification assay. During the 5-minute run, Mobile Phase A comprised 10 mM ammonium formate and 0.1% formic acid in LC-MS grade water. Mobile Phase B contained 10 mM ammonium formate and 0.1% formic acid in LC-MS grade water/acetonitrile/isopropanol (5%: 47.5%: 47.5%) (A) . Ceramide metabolites and internal standards were separated adequately based on molecular weights and polarities ( B - C ). The stability of ceramide metabolites over three freeze/thaw cycles showed percentage changes represented by blue, orange, and grey bars after 24, 48, and 72 h, respectively. Quality control levels confirmed percentage changes within ± 7% for all metabolites CerC16:0 ( D ), CerC18:0 ( E ), CerC22:0 ( F ), CerC24:0 ( G ), and CerC24:1 ( H ). Overlaid chromatograms of blank samples ( I ) confirmed method specificity, showing no interfering peaks at the respective retention times for ceramide metabolites. IS, Internal Standard; %change, stability

    Techniques Used: Liquid Chromatography, Mass Spectrometry, Liquid Chromatography with Mass Spectroscopy, Control

    The Multiple Reaction Monitoring (MRM) parameters of ceramide metabolites and corresponding internal standards
    Figure Legend Snippet: The Multiple Reaction Monitoring (MRM) parameters of ceramide metabolites and corresponding internal standards

    Techniques Used: Targeted Proteomics

    The liquid chromatography-mass spectrometry (LC-MS/MS) ceramide quantification assay validation results
    Figure Legend Snippet: The liquid chromatography-mass spectrometry (LC-MS/MS) ceramide quantification assay validation results

    Techniques Used: Chromatography, Biomarker Discovery, Concentration Assay

    Comparative results of the liquid chromatography-mass spectrometry (LC-MS/MS) ceramide quantification assay in this study and other relevant studies
    Figure Legend Snippet: Comparative results of the liquid chromatography-mass spectrometry (LC-MS/MS) ceramide quantification assay in this study and other relevant studies

    Techniques Used: Chromatography, Extraction, Solvent, Injection, Modification

    Median and 95% reference ranges of plasma ceramide levels and ratios in individuals aged 6–17 years
    Figure Legend Snippet: Median and 95% reference ranges of plasma ceramide levels and ratios in individuals aged 6–17 years

    Techniques Used: Clinical Proteomics



    Similar Products

    cerc24  (Croda International Plc)
    94
    Croda International Plc cerc24
    Integrated chromatograms, stability, and specificity of the liquid chromatography-mass spectrometry (LC-MS/MS) ceramide quantification assay. During the 5-minute run, Mobile Phase A comprised 10 mM ammonium formate and 0.1% formic acid in LC-MS grade water. Mobile Phase B contained 10 mM ammonium formate and 0.1% formic acid in LC-MS grade water/acetonitrile/isopropanol (5%: 47.5%: 47.5%) (A) . Ceramide metabolites and internal standards were separated adequately based on molecular weights and polarities ( B - C ). The stability of ceramide metabolites over three freeze/thaw cycles showed percentage changes represented by blue, orange, and grey bars after 24, 48, and 72 h, respectively. Quality control levels confirmed percentage changes within ± 7% for all metabolites CerC16:0 ( D ), CerC18:0 ( E ), CerC22:0 ( F ), <t>CerC24:0</t> ( G ), and CerC24:1 ( H ). Overlaid chromatograms of blank samples ( I ) confirmed method specificity, showing no interfering peaks at the respective retention times for ceramide metabolites. IS, Internal Standard; %change, stability
    Cerc24, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cerc24/product/Croda International Plc
    Average 94 stars, based on 1 article reviews
    cerc24 - by Bioz Stars, 2026-02
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    Integrated chromatograms, stability, and specificity of the liquid chromatography-mass spectrometry (LC-MS/MS) ceramide quantification assay. During the 5-minute run, Mobile Phase A comprised 10 mM ammonium formate and 0.1% formic acid in LC-MS grade water. Mobile Phase B contained 10 mM ammonium formate and 0.1% formic acid in LC-MS grade water/acetonitrile/isopropanol (5%: 47.5%: 47.5%) (A) . Ceramide metabolites and internal standards were separated adequately based on molecular weights and polarities ( B - C ). The stability of ceramide metabolites over three freeze/thaw cycles showed percentage changes represented by blue, orange, and grey bars after 24, 48, and 72 h, respectively. Quality control levels confirmed percentage changes within ± 7% for all metabolites CerC16:0 ( D ), CerC18:0 ( E ), CerC22:0 ( F ), CerC24:0 ( G ), and CerC24:1 ( H ). Overlaid chromatograms of blank samples ( I ) confirmed method specificity, showing no interfering peaks at the respective retention times for ceramide metabolites. IS, Internal Standard; %change, stability

    Journal: Lipids in Health and Disease

    Article Title: Circulating ceramide levels and ratios in Emirati youth under 18 years: associations with cardiometabolic risk factors

    doi: 10.1186/s12944-024-02080-6

    Figure Lengend Snippet: Integrated chromatograms, stability, and specificity of the liquid chromatography-mass spectrometry (LC-MS/MS) ceramide quantification assay. During the 5-minute run, Mobile Phase A comprised 10 mM ammonium formate and 0.1% formic acid in LC-MS grade water. Mobile Phase B contained 10 mM ammonium formate and 0.1% formic acid in LC-MS grade water/acetonitrile/isopropanol (5%: 47.5%: 47.5%) (A) . Ceramide metabolites and internal standards were separated adequately based on molecular weights and polarities ( B - C ). The stability of ceramide metabolites over three freeze/thaw cycles showed percentage changes represented by blue, orange, and grey bars after 24, 48, and 72 h, respectively. Quality control levels confirmed percentage changes within ± 7% for all metabolites CerC16:0 ( D ), CerC18:0 ( E ), CerC22:0 ( F ), CerC24:0 ( G ), and CerC24:1 ( H ). Overlaid chromatograms of blank samples ( I ) confirmed method specificity, showing no interfering peaks at the respective retention times for ceramide metabolites. IS, Internal Standard; %change, stability

    Article Snippet: The powder forms of Cer internal standards CerC16:0-d7 [C16:0-ceramide-d7 (d18:1-d7/16:0)], CerC18:0-d7 [C18:0-ceramide-d7 (d18:1-d7/18:0)], CerC24:0-d7 [C24:0-ceramide-d7 (d18:1-d7/24:0)], CerC24:1-d7 [C24:1-ceramide-d7 (d18:1-d7/24:1(15Z))] were also purchased from Avanti Polar Lipids [Alabaster, AL].

    Techniques: Liquid Chromatography, Mass Spectrometry, Liquid Chromatography with Mass Spectroscopy, Control

    The Multiple Reaction Monitoring (MRM) parameters of ceramide metabolites and corresponding internal standards

    Journal: Lipids in Health and Disease

    Article Title: Circulating ceramide levels and ratios in Emirati youth under 18 years: associations with cardiometabolic risk factors

    doi: 10.1186/s12944-024-02080-6

    Figure Lengend Snippet: The Multiple Reaction Monitoring (MRM) parameters of ceramide metabolites and corresponding internal standards

    Article Snippet: The powder forms of Cer internal standards CerC16:0-d7 [C16:0-ceramide-d7 (d18:1-d7/16:0)], CerC18:0-d7 [C18:0-ceramide-d7 (d18:1-d7/18:0)], CerC24:0-d7 [C24:0-ceramide-d7 (d18:1-d7/24:0)], CerC24:1-d7 [C24:1-ceramide-d7 (d18:1-d7/24:1(15Z))] were also purchased from Avanti Polar Lipids [Alabaster, AL].

    Techniques: Targeted Proteomics

    The liquid chromatography-mass spectrometry (LC-MS/MS) ceramide quantification assay validation results

    Journal: Lipids in Health and Disease

    Article Title: Circulating ceramide levels and ratios in Emirati youth under 18 years: associations with cardiometabolic risk factors

    doi: 10.1186/s12944-024-02080-6

    Figure Lengend Snippet: The liquid chromatography-mass spectrometry (LC-MS/MS) ceramide quantification assay validation results

    Article Snippet: The powder forms of Cer internal standards CerC16:0-d7 [C16:0-ceramide-d7 (d18:1-d7/16:0)], CerC18:0-d7 [C18:0-ceramide-d7 (d18:1-d7/18:0)], CerC24:0-d7 [C24:0-ceramide-d7 (d18:1-d7/24:0)], CerC24:1-d7 [C24:1-ceramide-d7 (d18:1-d7/24:1(15Z))] were also purchased from Avanti Polar Lipids [Alabaster, AL].

    Techniques: Chromatography, Biomarker Discovery, Concentration Assay

    Comparative results of the liquid chromatography-mass spectrometry (LC-MS/MS) ceramide quantification assay in this study and other relevant studies

    Journal: Lipids in Health and Disease

    Article Title: Circulating ceramide levels and ratios in Emirati youth under 18 years: associations with cardiometabolic risk factors

    doi: 10.1186/s12944-024-02080-6

    Figure Lengend Snippet: Comparative results of the liquid chromatography-mass spectrometry (LC-MS/MS) ceramide quantification assay in this study and other relevant studies

    Article Snippet: The powder forms of Cer internal standards CerC16:0-d7 [C16:0-ceramide-d7 (d18:1-d7/16:0)], CerC18:0-d7 [C18:0-ceramide-d7 (d18:1-d7/18:0)], CerC24:0-d7 [C24:0-ceramide-d7 (d18:1-d7/24:0)], CerC24:1-d7 [C24:1-ceramide-d7 (d18:1-d7/24:1(15Z))] were also purchased from Avanti Polar Lipids [Alabaster, AL].

    Techniques: Chromatography, Extraction, Solvent, Injection, Modification

    Median and 95% reference ranges of plasma ceramide levels and ratios in individuals aged 6–17 years

    Journal: Lipids in Health and Disease

    Article Title: Circulating ceramide levels and ratios in Emirati youth under 18 years: associations with cardiometabolic risk factors

    doi: 10.1186/s12944-024-02080-6

    Figure Lengend Snippet: Median and 95% reference ranges of plasma ceramide levels and ratios in individuals aged 6–17 years

    Article Snippet: The powder forms of Cer internal standards CerC16:0-d7 [C16:0-ceramide-d7 (d18:1-d7/16:0)], CerC18:0-d7 [C18:0-ceramide-d7 (d18:1-d7/18:0)], CerC24:0-d7 [C24:0-ceramide-d7 (d18:1-d7/24:0)], CerC24:1-d7 [C24:1-ceramide-d7 (d18:1-d7/24:1(15Z))] were also purchased from Avanti Polar Lipids [Alabaster, AL].

    Techniques: Clinical Proteomics